Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress--preliminary findings.

Depression is associated with an unusually high rate of aging-related illnesses and early mortality. One aspect of "accelerated aging" in depression may be shortened leukocyte telomeres. When telomeres critically shorten, as often occurs with repeated mitoses or in response to oxidation an...

Full description

Bibliographic Details
Main Authors: Owen M Wolkowitz, Synthia H Mellon, Elissa S Epel, Jue Lin, Firdaus S Dhabhar, Yali Su, Victor I Reus, Rebecca Rosser, Heather M Burke, Eve Kupferman, Mariana Compagnone, J Craig Nelson, Elizabeth H Blackburn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3063175?pdf=render