Claudin-Low Breast Cancer Inflammatory Signatures Support Polarization of M1-Like Macrophages with Protumoral Activity

Claudin-Low Breast Cancer Inflammatory Signatures Support Polarization of M1-Like Macrophages with Protumoral Activity

We previously reported that triple-negative breast cancer (BRCA) cells overexpress the cytokines GM-CSF, G-CSF, MCP-1, and RANTES, and when monocytes were 3-D co-cultured with them, M1-like macrophages were generated with the ability to induce aggressive features in luminal BRCA cell lines. These in...

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Bibliographic Details
Main Authors: Mayra Cecilia Suárez-Arriaga, Alfonso Méndez-Tenorio, Vadim Pérez-Koldenkova, Ezequiel M. Fuentes-Pananá
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
M1-like macrophages
protumoral activity
breast cancer
claudin-low
tumor microenvironment
Online Access:https://www.mdpi.com/2072-6694/13/9/2248

Internet

https://www.mdpi.com/2072-6694/13/9/2248

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