Ankyrin-G participates in INa remodeling in myocytes from the border zones of infarcted canine heart.

Cardiac Na channel remodeling provides a critical substrate for generation of reentrant arrhythmias in border zones of the infarcted canine heart. Recent studies show that Nav1.5 assembly and function are linked to ankyrin-G, gap, and mechanical junction proteins. In this study our objective is to e...

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Bibliographic Details
Main Authors: Wen Dun, John S Lowe, Patrick Wright, Thomas J Hund, Peter J Mohler, Penelope A Boyden
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3796465?pdf=render