Anti-gastric cancer effect of a novel small molecule inhibitor 1-3-51 targeting FOXM1 in vitro

Anti-gastric cancer effect of a novel small molecule inhibitor 1-3-51 targeting FOXM1 in vitro

Objective To investigate the role of a novel small molecule inhibitor 1-3-51 in the regulation of FOXM1 expression and its anticancer effect in gastric cancer. Methods CCK-8 assay was employed to measure the IC50 values in gastric cancer BGC823 and MKN45 cells after 1-3-51 treatment. Western blottin...

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Bibliographic Details
Main Authors: GAO Mengyuan, GU Jing, LUO Ya, TANG Qingyun, ZHANG Shengwei, HU Changjiang, OUYANG Qin, YANG Shiming
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2021-05-01
Series:Di-san junyi daxue xuebao
Subjects:
small molecule inhibitor
foxm1
proliferation
migration
invasion
gastric cancer
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202012068.htm

Internet

http://aammt.tmmu.edu.cn/Upload/rhtml/202012068.htm

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