Crystal structure of human interleukin-2 in complex with TCB2, a new antibody-drug candidate with antitumor activity

Immunotherapy via interleukin-2 (IL-2) mediated activation of anti-tumor immune response is a promising approach for cancer treatment. The multi-potent cytokine, IL-2 has a central role in immune cell activation and homeostasis. Since IL-2 preferentially activates immunosuppressive T regulatory cell...

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Bibliographic Details
Main Authors: Jieun Kim, Jun-Young Lee, Suk-Youl Park, You Jeong Lee, Min-Sung Kim
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:OncoImmunology
Subjects:
Online Access:http://dx.doi.org/10.1080/2162402X.2021.1899671