Protective Effect of Bruguiera gymnorrhiza (L.) Lam. Fruit on Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice: Role of Keap1/Nrf2 Pathway and Gut Microbiota

Protective Effect of Bruguiera gymnorrhiza (L.) Lam. Fruit on Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice: Role of Keap1/Nrf2 Pathway and Gut Microbiota

Bruguiera gymnorrhiza (BG), a medicinal mangrove, and its fruit (a food material) (BGF), have traditionally been used to treat diarrhea (also known as ulcerative colitis) in folk medicine. However, the mechanism of action against colitis remains ambiguous. This study aimed to investigate the potenti...

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Bibliographic Details
Main Authors: Yinsi Lin, Xinghan Zheng, Jinfen Chen, Dandan Luo, Jianhui Xie, Ziren Su, Xiaoqi Huang, Xiaoqing Yi, Long Wei, Jian Cai, Zhanghua Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Pharmacology
Subjects:
Bruguiera gymnorrhiza
ulcerative colitis
pinitol
Keap1/Nrf2
gut microbiota
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01602/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01602/full

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