Mutations in SIX1 Associated with Branchio-oto-Renal Syndrome (BOR) Differentially Affect Otic Expression of Putative Target Genes

Mutations in SIX1 Associated with Branchio-oto-Renal Syndrome (BOR) Differentially Affect Otic Expression of Putative Target Genes

Several single-nucleotide mutations in <i>SIX1</i> underlie branchio-otic/branchio-oto-renal (BOR) syndrome, but the clinical literature has not been able to correlate different variants with specific phenotypes. We previously assessed whether variants in either the cofactor binding doma...

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Bibliographic Details
Main Authors: Tanya Mehdizadeh, Himani D. Majumdar, Sarah Ahsan, Andre L. P. Tavares, Sally A. Moody
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Journal of Developmental Biology
Subjects:
neural crest
cranial placodes
transcription
<i>Xenopus</i>
Online Access:https://www.mdpi.com/2221-3759/9/3/25

Internet

https://www.mdpi.com/2221-3759/9/3/25

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