Genetic Alterations in Benign Breast Biopsies of Subsequent Breast Cancer Patients

Genetic Alterations in Benign Breast Biopsies of Subsequent Breast Cancer Patients

Background: Fibrocystic changes are associated with an increased risk of breast cancer. Genetic alterations have been found in fibrocystic changes with or without epithelial changes, suggesting that critical oncogenic events are occurring at an early stage.Methods: We investigated a unique collectiv...

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Bibliographic Details
Main Authors: Savas D. Soysal, Charlotte K. Y. Ng, Luigi Costa, Walter P. Weber, Viola Paradiso, Salvatore Piscuoglio, Simone Muenst
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Medicine
Subjects:
breast cancer
genetic alteration
fibrocystic mastopathy
carcinogenesis
somatic mutation
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2019.00166/full

Internet

https://www.frontiersin.org/article/10.3389/fmed.2019.00166/full

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