Polymorphism in ERCC1 confers susceptibility of coronary artery disease and severity of coronary artery atherosclerosis in a Chinese Han population

Abstract Excision repair cross-complementing 1 (ERCC1) gene encodes ERCC1 protein, which is mainly responsible for the repair of DNA damage in different diseases including coronary artery atherosclerosis by acting as a rate-limiting element in nucleotide excision repair (NER). Using a three-stage ca...

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Bibliographic Details
Main Authors: Shuai Zhang, Xue-bin Wang, Ya-di Han, Chen-ling Xiong, Ye Zhou, Chen Wang, Ze-jin Liu, Na Yang, Fang Zheng
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06732-9