Decreased expression of the clock gene Bmal1 is involved in the pathogenesis of temporal lobe epilepsy

Decreased expression of the clock gene Bmal1 is involved in the pathogenesis of temporal lobe epilepsy

Abstract Clock genes not only regulate the circadian rhythm of physiological activities but also participate in the pathogenesis of many diseases. Previous studies have documented the abnormal expression of clock genes in epilepsy. However, the molecular mechanism of brain and muscle Arnt-like prote...

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Bibliographic Details
Main Authors: Hao Wu, Yong Liu, Lishuo Liu, Qiang Meng, Changwang Du, Kuo Li, Shan Dong, Yong Zhang, Huanfa Li, Hua Zhang
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Molecular Brain
Subjects:
Clock genes
Bmal1
Protocadherin 19
Dentate gyrus
Temporal lobe epilepsy
Transgenic mice
Online Access:https://doi.org/10.1186/s13041-021-00824-4

Internet

https://doi.org/10.1186/s13041-021-00824-4

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