Human Liver Stem Cell-Derived Extracellular Vesicles Prevent Aristolochic Acid-Induced Kidney Fibrosis

Human Liver Stem Cell-Derived Extracellular Vesicles Prevent Aristolochic Acid-Induced Kidney Fibrosis

With limited therapeutic intervention in preventing the progression to end-stage renal disease, chronic kidney disease (CKD) remains a global health-care burden. Aristolochic acid (AA) induced nephropathy is a model of CKD characterised by inflammation, tubular injury, and interstitial fibrosis. Hum...

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Bibliographic Details
Main Authors: Sharad Kholia, Maria Beatriz Herrera Sanchez, Massimo Cedrino, Elli Papadimitriou, Marta Tapparo, Maria Chiara Deregibus, Maria Felice Brizzi, Ciro Tetta, Giovanni Camussi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
aristolochic acid nephropathy
extracellular vesicles
human liver stem cells
chronic kidney disease
miRNA
fibrosis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01639/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01639/full

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