AF10 plays a key role in the survival of uncommitted hematopoietic cells.

Hematopoiesis is a complex process regulated by both cell intrinsic and cell extrinsic factors. Alterations in the expression of critical genes during hematopoiesis can modify the balance between stem cell differentiation and proliferation, and may ultimately give rise to leukemia and other diseases...

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Bibliographic Details
Main Authors: Raquel Chamorro-Garcia, Margarita Cervera, Juan J Arredondo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3526614?pdf=render