Molecular mechanisms that regulate the macrophage M1/M2 polarization balance

As an essential component of innate immunity, macrophages have multiple functions in both inhibiting or promoting cell proliferation and tissue repair. Diversity and plasticity are hallmarks of macrophages. Classical M1 and alternative M2 activation of macrophages, mirroring the Th1–Th2 polarization...

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Bibliographic Details
Main Authors: Nan eWang, Hongwei eLiang, Ke eZen
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Immunology
Subjects:
TLR
NLR
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00614/full