Conversion of dietary inositol into propionate and acetate by commensal Anaerostipes associates with host health

Here, the authors report an anaerobic metabolic pathway from the dominant gut butyrogen Anaerostipes, showing several strains of this genus to be capable of producing propionate from dietary myo-inositol that associates with reduced fasting-glucose levels in mice.

Bibliographic Details
Main Authors: Thi Phuong Nam Bui, Louise Mannerås-Holm, Robert Puschmann, Hao Wu, Antonio Dario Troise, Bart Nijsse, Sjef Boeren, Fredrik Bäckhed, Dorothea Fiedler, Willem M. deVos
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-25081-w