Synthetic chemistry with friendships that unveiled the long-lasting mystery of lipid A

Endotoxin research in recent years at the molecular level has required chemically synthesized lipid A without contamination by other bioactive components. Total synthesis of Escherichia coli -type lipid A was achieved in the 1980s by the challenging spirits of the scientists at Osaka University, Jap...

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Bibliographic Details
Main Author: Kazuyoshi Kawahara
Format: Article
Language:English
Published: SAGE Publishing 2019-04-01
Series:Innate Immunity
Online Access:https://doi.org/10.1177/1753425919835298