Primed T cell responses to chemokines are regulated by the immunoglobulin-like molecule CD31.

CD31, an immunoglobulin-like molecule expressed by leukocytes and endothelial cells, is thought to contribute to the physiological regulation T cell homeostasis due to the presence of two immunotyrosine-based inhibitory motifs in its cytoplasmic tail. Indeed, loss of CD31 expression leads to uncontr...

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Bibliographic Details
Main Authors: Madhav Kishore, Liang Ma, Georgina Cornish, Sussan Nourshargh, Federica M Marelli-Berg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3378580?pdf=render