Pair-wise regulation of convergence and extension cell movements by four phosphatases via RhoA.

Various signaling pathways regulate shaping of the main body axis during early vertebrate development. Here, we focused on the role of protein-tyrosine phosphatase signaling in convergence and extension cell movements. We identified Ptpn20 as a structural paralogue of PTP-BL and both phosphatases we...

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Bibliographic Details
Main Authors: Mark van Eekelen, Vincent Runtuwene, Wouter Masselink, Jeroen den Hertog
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3335823?pdf=render