Cross species association examination of UCN3 and CRHR2 as potential pharmacological targets for antiobesity drugs.

BACKGROUND: Obesity now constitutes a leading global public health problem. Studies have shown that insulin resistance affiliated with obesity is associated with intramyocellular lipid (IMCL) accumulation. Therefore, identification of genes associated with the phenotype would provide a clear target...

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Bibliographic Details
Main Authors: Zhihua Jiang, Jennifer J Michal, Galen A Williams, Tyler F Daniels, Tanja Kunej
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1762311?pdf=render