Palmitoylation regulates epidermal homeostasis and hair follicle differentiation.

Palmitoylation regulates epidermal homeostasis and hair follicle differentiation.

Palmitoylation is a key post-translational modification mediated by a family of DHHC-containing palmitoyl acyl-transferases (PATs). Unlike other lipid modifications, palmitoylation is reversible and thus often regulates dynamic protein interactions. We find that the mouse hair loss mutant, depilated...

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Bibliographic Details
Main Authors: Pleasantine Mill, Angela W S Lee, Yuko Fukata, Ryouhei Tsutsumi, Masaki Fukata, Margaret Keighren, Rebecca M Porter, Lisa McKie, Ian Smyth, Ian J Jackson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2776530?pdf=render

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http://europepmc.org/articles/PMC2776530?pdf=render

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