Treating hematological malignancies with drugs inhibiting ribosome biogenesis: when and why

Abstract It is well known that chemotherapy can cure only some cancers in advanced stage, mostly those with an intact p53 pathway. Hematological cancers such as lymphoma and certain forms of leukemia are paradigmatic examples of such scenario. Recent evidence indicates that the efficacy of many of t...

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Bibliographic Details
Main Authors: Enrico Derenzini, Alessandra Rossi, Davide Treré
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13045-018-0609-1