Genomic scanning enabling discovery of a new antibacterial bicyclic carbamate-containing alkaloid

Genomic scanning enabling discovery of a new antibacterial bicyclic carbamate-containing alkaloid

Non-ribosomal peptides are a group of structurally diverse natural products with various important therapeutic and agrochemical applications. Bacterial pyrrolizidine alkaloids (PAs), containing a scaffold of two fused five-membered ring system with a nitrogen atom at the bridgehead, have been found...

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Bibliographic Details
Main Authors: Qing Fang, Linrui Wu, Caroline Urwald, Morgane Mugat, Shan Wang, Kwaku Kyeremeh, Carol Philips, Samantha Law, Yongjun Zhou, Hai Deng
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-03-01
Series:Synthetic and Systems Biotechnology
Subjects:
Genomic scanning
Bayer villiger monooxygenase
Carbamate alkaloids
Pyrrolizidine alkaloids
Non-ribosomal peptide synthetases
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X21000028

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http://www.sciencedirect.com/science/article/pii/S2405805X21000028

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