Neo-synthesis of estrogenic or androgenic neurosteroids determine whether long-term potentiation or depression is induced in hippocampus of male rat

Neo-synthesis of estrogenic or androgenic neurosteroids determine whether long-term potentiation or depression is induced in hippocampus of male rat

Estrogenic and androgenic steroids synthesized in the brain may rapidly modulate synaptic plasticity interacting with specific membrane receptors. We explored by electrophysiological recordings in hippocampal slices of male rat the influence of 17b-estradiol (E2) and 5a-dihydrotestosterone (DHT) neo...

Full description

Bibliographic Details
Main Authors: Michela eDi Mauro, Alessandro eTozzi, Paolo eCalabresi, Vito Enrico Pettorossi, Silvarosa eGrassi
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Hippocampus
Long-Term Potentiation
Long-term depression
17β-estradiol
depotentiation
P450-aromatase
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00376/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00376/full

Similar Items