Efficacy and Immune Mechanisms of Cetuximab for the Treatment of Metastatic Colorectal Cancer
Cetuximab is a chimeric immunoglobulin G1 mono-clonal antibody that targets the ligand-binding domain of the epidermal growth factor receptor and inhibits downstream intra- cellular signals. Research has shown that etuximab can stimulate the autoimmune system and produce antibody-dependent cellular...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
China Anti-Cancer Association
2011-12-01
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| Series: | Cancer Biology & Medicine |
| Subjects: | |
| Online Access: | http://www.cancerbiomed.org/index.php/cocr/article/view/76 |