Pin1 Modulation in Physiological Status and Neurodegeneration. Any Contribution to the Pathogenesis of Type 3 Diabetes?

Pin1 Modulation in Physiological Status and Neurodegeneration. Any Contribution to the Pathogenesis of Type 3 Diabetes?

Prolyl isomerases (Peptidylprolyl isomerase, PPIases) are enzymes that catalyze the isomerization between the cis/trans Pro conformations. Three subclasses belong to the class: FKBP (FK506 binding protein family), Cyclophilin and Parvulin family (Pin1 and Par14). Among Prolyl isomerases, Pin1 presen...

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Bibliographic Details
Main Authors: Marzia Bianchi, Melania Manco
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s disease
brain glucose metabolism
neuronal differentiation
neuronal degeneration
Prolyl isomerases
Pin1
type 2 diabetes
type 3 diabetes
Online Access:http://www.mdpi.com/1422-0067/19/8/2319

Internet

http://www.mdpi.com/1422-0067/19/8/2319

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