Cholera toxin B subunits assemble into pentamers--proposition of a fly-casting mechanism.

The cholera toxin B pentamer (CtxB(5)), which belongs to the AB(5) toxin family, is used as a model study for protein assembly. The effect of the pH on the reassembly of the toxin was investigated using immunochemical, electrophoretic and spectroscopic methods. Three pH-dependent steps were identifi...

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Bibliographic Details
Main Authors: Jihad Zrimi, Alicia Ng Ling, Ernawati Giri-Rachman Arifin, Giovanni Feverati, Claire Lesieur
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3006222?pdf=render