Culture of <i>Mycobacterium smegmatis</i> in Different Carbon Sources to Induce In Vitro Cholesterol Consumption Leads to Alterations in the Host Cells after Infection: A Macrophage Proteomics Analysis

Culture of <i>Mycobacterium smegmatis</i> in Different Carbon Sources to Induce In Vitro Cholesterol Consumption Leads to Alterations in the Host Cells after Infection: A Macrophage Proteomics Analysis

During tuberculosis, <i>Mycobacterium</i> uses host macrophage cholesterol as a carbon and energy source. To mimic these conditions, <i>Mycobacterium smegmatis</i> can be cultured in minimal medium (MM) to induce cholesterol consumption in vitro. During cultivation, <i>...

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Bibliographic Details
Main Authors: Jaqueline Batista de Lima, Lana Patricia da Silva Fonseca, Luciana Pereira Xavier, Barbarella de Matos Macchi, Juliana Silva Cassoli, Edilene Oliveira da Silva, Rafael Borges da Silva Valadares, José Luiz Martins do Nascimento, Agenor Valadares Santos, Chubert Bernardo Castro de Sena
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Pathogens
Subjects:
<i>Mycobacterium</i>
proteomics
cholesterol
infection
macrophages
Online Access:https://www.mdpi.com/2076-0817/10/6/662

Internet

https://www.mdpi.com/2076-0817/10/6/662

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