Strategies for the inhibition of gingipains for the potential treatment of periodontitis and associated systemic diseases

Gingipains are the major virulence factors of Porphyromonas gingivalis, the main periodontopathogen. It is expected that inhibition of gingipain activity in vivo could prevent or slow down the progression of adult periodontitis. To date, several classes of gingipain inhibitors have been recognized....

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Bibliographic Details
Main Authors: Ingar Olsen, Jan Potempa
Format: Article
Language:English
Published: Taylor & Francis Group 2014-08-01
Series:Journal of Oral Microbiology
Subjects:
Online Access:http://www.journaloforalmicrobiology.net/index.php/jom/article/download/24800/35178