Concordant and discordant regulation of target genes by miR-31 and its isoforms.

It has been shown that imprecise cleavage of a primary or precursor RNA by Drosha or Dicer, respectively, may yield a group of microRNA (miRNA) variants designated as "isomiR". Variations in the relative abundance of isoforms for a given miRNA among different species and different cell typ...

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Bibliographic Details
Main Authors: Yu-Tzu Chan, You-Chin Lin, Ruey-Jen Lin, Huan-Hsien Kuo, Wai-Cheng Thang, Kuo-Ping Chiu, Alice L Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3589381?pdf=render