Ultrasonic-assisted unusual four-component synthesis of 7-azolylamino-4,5,6,7-tetrahydroazolo[1,5-a]pyrimidines

Ultrasonic-assisted unusual four-component synthesis of 7-azolylamino-4,5,6,7-tetrahydroazolo[1,5-a]pyrimidines

Four-component reactions of 3-amino-1,2,4-triazole or 5-amino-1H-pyrazole-4-carbonitrile with aromatic aldehydes and pyruvic acid or its esters under ultrasonication were studied. Unusual for such a reaction type, a cascade of elementary stages led to the formation of 7-azolylaminotetrahydroazolo[1,...

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Bibliographic Details
Main Authors: Yana I. Sakhno, Maryna V. Murlykina, Oleksandr I. Zbruyev, Anton V. Kozyryev, Svetlana V. Shishkina, Dmytro Sysoiev, Vladimir I. Musatov, Sergey M. Desenko, Valentyn A. Chebanov
Format: Article
Language:English
Published: Beilstein-Institut 2020-02-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
5-amino-1h-pyrazole-4-carbonitrile
3-amino-1,2,4-triazole
7-azolylaminotetrahydroazolo[1,5-a]pyrimidines
heterocycle
multicomponent reaction
ultrasonication
Online Access:https://doi.org/10.3762/bjoc.16.27

Internet

https://doi.org/10.3762/bjoc.16.27

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