CARD8 SNP rs11672725 Identified as a Potential Genetic Variant for Adult-Onset Still’s Disease

CARD8 SNP rs11672725 Identified as a Potential Genetic Variant for Adult-Onset Still’s Disease

Adult-onset Still’s disease (AOSD), an autoinflammatory disorder, is related to the dysregulation of NLR3-containing a pyrin domain (NLRP3)-inflammasome signaling. We aimed to investigate the associations of genetic polymorphisms of NLRP3-inflammasome signaling with AOSD susceptibility and outcome a...

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Bibliographic Details
Main Authors: Wei-Ting Hung, Yi-Ming Chen, Shuen-Iu Hung, Hsin-Hua Chen, Ning-Rong Gung, Chia-Wei Hsieh, Kuo-Tung Tang, Der-Yuan Chen
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Life
Subjects:
CARD8
single-nucleotide polymorphism
rs11672725
NLRP3-inflammasome signaling
adult-onset Still’s disease (AOSD)
Online Access:https://www.mdpi.com/2075-1729/11/5/382

Internet

https://www.mdpi.com/2075-1729/11/5/382

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