Extracellular matrix surface regulates self-assembly of three-dimensional placental trophoblast spheroids.

The incorporation of the extracellular matrix (ECM) is essential for generating in vitro models that truly represent the microarchitecture found in human tissues. However, the cell-cell and cell-ECM interactions in vitro remains poorly understood in placental trophoblast biology. We investigated the...

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Bibliographic Details
Main Authors: Michael K Wong, Sarah A Shawky, Aditya Aryasomayajula, Madeline A Green, Tom Ewart, P Ravi Selvaganapathy, Sandeep Raha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6016924?pdf=render