Inflammatory Dendritic Cells Contribute to Regulate the Immune Response in Sickle Cell Disease

Inflammatory Dendritic Cells Contribute to Regulate the Immune Response in Sickle Cell Disease

Sickle cell disease (SCD), one of the most common hemoglobinopathies worldwide, is characterized by a chronic inflammatory component, with systemic release of inflammatory cytokines, due to hemolysis and vaso-occlusive processes. Patients with SCD demonstrate dysfunctional T and B lymphocyte respons...

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Bibliographic Details
Main Authors: Renata Sesti-Costa, Marina Dorigatti Borges, Carolina Lanaro, Dulcinéia Martins de Albuquerque, Sara Terezinha Olalla Saad, Fernando Ferreira Costa
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
dendritic cell
sickle cell disease
heme oxygenase
inflammation
monocyte
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.617962/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.617962/full

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