Aurora kinases in ovarian cancer

Aurora kinases (AURK) are key regulators of the mitotic spindle formation. AURK is frequently overexpressed in ovarian cancer and this overexpression has been frequently associated with prognosis in these tumours. Interestingly, AURK have been shown to interact with DNA repair mechanisms and other c...

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Bibliographic Details
Main Authors: Valentina Gambardella, Andrés Cervantes, J Alejandro Pérez-Fidalgo, Begoña Pineda, Octavio Burgues, Oscar Piñero
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:ESMO Open
Online Access:https://esmoopen.bmj.com/content/5/5/e000718.full