Lack of stearoyl-CoA desaturase-1 function induces a palmitoyl-CoA Δ6 desaturase and represses the stearoyl-CoA desaturase-3 gene in the preputial glands of the mouse

Lack of stearoyl-CoA desaturase-1 function induces a palmitoyl-CoA Δ6 desaturase and represses the stearoyl-CoA desaturase-3 gene in the preputial glands of the mouse

The mouse preputial gland (222298), a specialized sebaceous structure, is rich in wax esters, triglycerides, and alkyl-2,3-diacylglycerol. We have found that the mouse PG expresses the three gene isoforms (SCD1, SCD2, and SCD3) of the Δ9 stearoyl-CoA desaturase enzyme that catalyzes the biosynthesis...

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Bibliographic Details
Main Authors: Makoto Miyazaki, Francisco Enrique Gomez, James M. Ntambi
Format: Article
Language:English
Published: Elsevier 2002-12-01
Series:Journal of Lipid Research
Subjects:
Δ6 hexadecenoic acid
wax esters
triglycerides
gene isoforms
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520327437

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http://www.sciencedirect.com/science/article/pii/S0022227520327437

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