Network-guided prediction of aromatase inhibitor response in breast cancer.

Prediction of response to specific cancer treatments is complicated by significant heterogeneity between tumors in terms of mutational profiles, gene expression, and clinical measures. Here we focus on the response of Estrogen Receptor (ER)+ post-menopausal breast cancer tumors to aromatase inhibito...

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Bibliographic Details
Main Authors: Matthew Ruffalo, Roby Thomas, Jian Chen, Adrian V Lee, Steffi Oesterreich, Ziv Bar-Joseph
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-02-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC6386390?pdf=render