Evaluation of an Internally Controlled Multiplex Tth Endonuclease Cleavage Loop-Mediated Isothermal Amplification (TEC-LAMP) Assay for the Detection of Bacterial Meningitis Pathogens

Evaluation of an Internally Controlled Multiplex Tth Endonuclease Cleavage Loop-Mediated Isothermal Amplification (TEC-LAMP) Assay for the Detection of Bacterial Meningitis Pathogens

Bacterial meningitis infection is a leading global health concern for which rapid and accurate diagnosis is essential to reduce associated morbidity and mortality. Loop-mediated isothermal amplification (LAMP) offers an effective low-cost diagnostic approach; however, multiplex LAMP is difficult to...

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Bibliographic Details
Main Authors: Owen Higgins, Eoin Clancy, Martin Cormican, Teck Wee Boo, Robert Cunney, Terry J. Smith
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:International Journal of Molecular Sciences
Subjects:
bacterial meningitis
nucleic acid diagnostics
loop-mediated isothermal amplification
multiplex
internal control
Online Access:http://www.mdpi.com/1422-0067/19/2/524

Internet

http://www.mdpi.com/1422-0067/19/2/524

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