Reduced paxillin expression contributes to the antimetastatic effect of 4-hydroxycoumarin on B16-F10 melanoma cells

<p>Abstract</p> <p>Background</p> <p>4-Hydroxycoumarin (4-HC) is a coumarin that lacks anticoagulant activity. 4-HC affects the cytoskeletal stability and decreases cell adhesion and motility of the melanoma cell line B16-F10. Together with integrins and other cytoskele...

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Bibliographic Details
Main Authors: Mandoki Juan J, Mendoza-Patiño Nicandro, Salinas-Jazmín Nohemí, Velasco-Velázquez Marco A
Format: Article
Language:English
Published: BMC 2008-05-01
Series:Cancer Cell International
Online Access:http://www.cancerci.com/content/8/1/8