Potentially functional polymorphism in IL-23 receptor and risk of acute myeloid leukemia in a Chinese population.

The interleukin-23 (IL-23) and its receptor (IL-23R) mediate the direct antitumor activities in human hematologic malignancies including pediatric acute leukemia. Two potentially functional genetic variants (IL-23R rs1884444 T>G and rs6682925 T>C) have been found to contribute to solid cancer...

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Bibliographic Details
Main Authors: Xifeng Qian, Songyu Cao, Guohua Yang, Yun Pan, Chenyu Yin, Xiang Chen, Ying Zhu, Yun Zhuang, Yunfeng Shen, Zhibin Hu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3564797?pdf=render