Melanoma-specific bcl-2 promotes a protumoral M2-like phenotype by tumor-associated macrophages

Melanoma-specific bcl-2 promotes a protumoral M2-like phenotype by tumor-associated macrophages

BackgroundA bidirectional crosstalk between tumor cells and the surrounding microenvironment contributes to tumor progression and response to therapy. Our previous studies have demonstrated that bcl-2 affects melanoma progression and regulates the tumor microenvironment. The aim of this study was to...

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Bibliographic Details
Main Authors: Antonio Sica, Marta Di Martile, Valentina Farini, Francesca Maria Consonni, Daniela Trisciuoglio, Marianna Desideri, Elisabetta Valentini, Simona D'Aguanno, Maria Grazia Tupone, Simonetta Buglioni, Cristiana Ercolani, Enzo Gallo, Bruno Amadio, Irene Terrenato, Maria Laura Foddai, Donatella Del Bufalo
Format: Article
Language:English
Published: BMJ Publishing Group 2020-06-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/1/e000489.full

Internet

https://jitc.bmj.com/content/8/1/e000489.full

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