The μ-opioid receptor gene and smoking initiation and nicotine dependence

<p>Abstract</p> <p>The gene encoding the mu-opioid receptor (OPRM1) is reported to be associated with a range of substance dependence. Experiments in knockout mice indicate that the mu-opioid receptor may mediate reinforcing effects of nicotine. In humans, opioid antagonist naltrex...

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Bibliographic Details
Main Authors: Kendler Kenneth S, Zhang Lan, Chen Xiangning
Format: Article
Language:English
Published: BMC 2006-08-01
Series:Behavioral and Brain Functions
Online Access:http://www.behavioralandbrainfunctions.com/content/2/1/28