NADPH promotes the rapid growth of the tumor

NADPH oxidase is the main source of intracellular reactive oxygen species (ROS). ROS plays an important role in a variety of tumor types. The ROS mediated by NADPH oxidase increases the expression of hypoxia-inducible factor alpha (HIF-α) through multiple signaling pathways in tumor, and HIF-α could...

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Bibliographic Details
Main Author: Hao Sheng
Format: Article
Language:English
Published: Sciendo 2018-04-01
Series:Infection International
Subjects:
ROS
Online Access:http://www.degruyter.com/view/j/ii.2017.6.issue-2/ii-2017-0164/ii-2017-0164.xml?format=INT