Genetic variations and haplotype diversity of the UGT1 gene cluster in the Chinese population.

Genetic variations and haplotype diversity of the UGT1 gene cluster in the Chinese population.

Vertebrates require tremendous molecular diversity to defend against numerous small hydrophobic chemicals. UDP-glucuronosyltransferases (UGTs) are a large family of detoxification enzymes that glucuronidate xenobiotics and endobiotics, facilitating their excretion from the body. The UGT1 gene cluste...

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Bibliographic Details
Main Authors: Jing Yang, Lei Cai, Haiyan Huang, Bingya Liu, Qiang Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3325998?pdf=render

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