Genetic variations and haplotype diversity of the UGT1 gene cluster in the Chinese population.

Vertebrates require tremendous molecular diversity to defend against numerous small hydrophobic chemicals. UDP-glucuronosyltransferases (UGTs) are a large family of detoxification enzymes that glucuronidate xenobiotics and endobiotics, facilitating their excretion from the body. The UGT1 gene cluste...

Full description

Bibliographic Details
Main Authors: Jing Yang, Lei Cai, Haiyan Huang, Bingya Liu, Qiang Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3325998?pdf=render