Saikosaponins induced hepatotoxicity in mice via lipid metabolism dysregulation and oxidative stress: a proteomic study

Saikosaponins induced hepatotoxicity in mice via lipid metabolism dysregulation and oxidative stress: a proteomic study

Abstract Background Radix Bupleuri (RB) has been popularly used for treating many liver diseases such as chronic hepatic inflammation and viral Hepatitis in China. Increasing clinical and experimental evidence indicates the potential hepatotoxicity of RB or prescriptions containing RB. Recently, Sai...

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Bibliographic Details
Main Authors: Xiaoyu Li, Xiaojiaoyang Li, Junxian Lu, Youyi Huang, Lili Lv, Yongfu Luan, Runping Liu, Rong Sun
Format: Article
Language:English
Published: BMC 2017-04-01
Series:BMC Complementary and Alternative Medicine
Subjects:
High Performance Liquid Chromatography
HepG2 Cell
Liver Injury
Acute Liver Injury
iTRAQ Labelling
Online Access:http://link.springer.com/article/10.1186/s12906-017-1733-0

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http://link.springer.com/article/10.1186/s12906-017-1733-0

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