Differential gene expression of tumor-infiltrating CD4+ T cells in advanced versus early stage colorectal cancer and identification of a gene signature of poor prognosis

Differential gene expression of tumor-infiltrating CD4+ T cells in advanced versus early stage colorectal cancer and identification of a gene signature of poor prognosis

Tumor-infiltrating lymphocytes (TILs) play indispensable roles in the progression and response to treatment of solid tumors. However, the prognostic significance of CD4+ TILs is not fully disclosed in cancers generally and in CRC in particular, mainly due to the existence of different functional sub...

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Bibliographic Details
Main Authors: Varun Sasidharan Nair, Reem Saleh, Rowaida Z Taha, Salman M Toor, Khaled Murshed, Ayman A Ahmed, Mohamed A Kurer, Mohamed Abu Nada, Fares Al Ejeh, Eyad Elkord
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:OncoImmunology
Subjects:
colorectal cancer
tumor-infiltrating lymphocytes
th1 immune response
chromatin silencing
predictive biomarkers
Online Access:http://dx.doi.org/10.1080/2162402X.2020.1825178

Internet

http://dx.doi.org/10.1080/2162402X.2020.1825178

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