Pro-inflammatory cytokines can act as intracellular modulators of commensal bacterial virulence

Pro-inflammatory cytokines can act as intracellular modulators of commensal bacterial virulence

Interactions between commensal pathogens and hosts are critical for disease development but the underlying mechanisms for switching between the commensal and virulent states are unknown. We show that the human pathogen Neisseria meningitidis, the leading cause of pyogenic meningitis, can modulate ge...

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Bibliographic Details
Main Authors: Jafar Mahdavi, Pierre-Joseph Royer, Hong S. Sjölinder, Sheyda Azimi, Tim Self, Jeroen Stoof, Lee M. Wheldon, Kristoffer Brännström, Raymond Wilson, Joanna Moreton, James W. B. Moir, Carina Sihlbom, Thomas Borén, Ann-Beth Jonsson, Panos Soultanas, Dlawer A. A. Ala'Aldeen
Format: Article
Language:English
Published: The Royal Society 2013-01-01
Series:Open Biology
Subjects:
neisseria meningitidis
type iv pili
glycosylation
cytokines
patho-adaptation
transcriptional regulators
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.130048

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https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.130048

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