Metformin Protects against Radiation-Induced Pneumonitis and Fibrosis and Attenuates Upregulation of Dual Oxidase Genes Expression

Metformin Protects against Radiation-Induced Pneumonitis and Fibrosis and Attenuates Upregulation of Dual Oxidase Genes Expression

Purpose: Lung tissue is one of the most sensitive organs to ionizing radiation (IR). Early and late side effects of exposure to IR can limit the radiation doses delivered to tumors that are within or adjacent to this organ. Pneumonitis and fibrosis are the main side effects of radiotherapy for this...

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Bibliographic Details
Main Authors: Rasoul Azmoonfar, Peyman Amini, Hana Saffar, Saeed Rezapoor, Elahe Motevaseli, Mohsen Cheki, Rasoul Yahyapour, Bagher farhood, Farzad Nouruzi, Ehsan Khodamoradi, Dheyauldeen Shabeeb, Ahmed Eleojo Musa, Masoud Najafi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2018-11-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Radiation
Metformin
Inflammation
Fibrosis
DUOX1
DUOX2
Online Access:https://apb.tbzmed.ac.ir/PDF/apb-20783

Internet

https://apb.tbzmed.ac.ir/PDF/apb-20783

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