H9N2 influenza virus acquires intravenous pathogenicity on the introduction of a pair of di-basic amino acid residues at the cleavage site of the hemagglutinin and consecutive passages in chickens

<p>Abstract</p> <p>Background</p> <p>Outbreaks of avian influenza (AI) caused by infection with low pathogenic H9N2 viruses have occurred in poultry, resulting in serious economic losses in Asia and the Middle East. It has been difficult to eradicate the H9N2 virus beca...

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Bibliographic Details
Main Authors: Sakoda Yoshihiro, Okamatsu Masatoshi, Asakura Shingo, Soda Kosuke, kida Hiroshi
Format: Article
Language:English
Published: BMC 2011-02-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/8/1/64