Mitochondrial peptide BRAWNIN is essential for vertebrate respiratory complex III assembly
Small open reading frame-encoded peptides (SEPs), shorter than 100 amino acids, are involved in many cell biological processes. Here the authors identify 16 nuclear-encoded mitochondrial SEPs, including BRAWNIN, an essential regulator of respiratory chain complex III assembly and ATP production.
Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-03-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-14999-2 |