Reversed phase parallel artificial membrane permeation assay for log P measurement
A reversed phase parallel artificial membrane permeation assay (RP-PAMPA) was newly invented for log P measurement. An oil/water/oil sandwich was constructed using a conventional PAMPA instrument. 1 % agarose was used to improve the physical stability of the water phase. A linear correlation between...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
International Association of Physical Chemists (IAPC)
2016-03-01
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Series: | ADMET and DMPK |
Online Access: | http://pub.iapchem.org/ojs/index.php/admet/article/view/277 |